Class Project

For the final project of BMI 273A (The Human Genome Source Code) taught by Dr. Gill Bejarano, I worked with a group to devise a statistic to measure how “mutable” a given exon is (some mutations impact the function of an exoonic product, while others do not, ie. synonymous vs. nonsynonymous mutations). We used the ExAC dataset to isolate exons and calculate an EMTM score, our version of the RVIS score. We presented our metric, and maintain the results, explorations, and code on GitHub.